@article{101463, keywords = {atypical cutaneous leishmaniasis, Leishmania donovani, Western Ghats}, author = {Fathima PA and Shah HK and Aiswarya RS and Ajithlal PM and Shailaja TV and Shubin C and Reena KJ and Saini P}, title = {Cutaneous leishmaniasis: a neglected clinical manifestation among the tribal population in Nilambur, Kerala, India}, abstract = {
Background: Different clinical manifestations of leishmaniasis (cutaneous and visceral) caused by Leishmania donovani have been reported from Kerala, India. Leishmania donovani causing cutaneous leishmaniasis (CL) (also called atypical CL [ACL]) is one of the major health concerns in the Western Ghats belt of the state.
Methods: Skin biopsies of 20 patients with suspected CL from Nilambur, Kerala, were processed for CL diagnosis during the period 2022–2023. Parasite species were characterized using Leishmania-specific Internal Transcribed Spacer-Ⅰ (ITS-Ⅰ) PCR and ITS-Ⅰ RFLP analysis.
Result: A total of 18 cases were confirmed to be CL and the parasite was identified as L. donovani.
Conclusion: These indigenous ACL (CL due to L. donovani) reports from the small foci of Nilambur reveal an emerging endemic zone of leishmaniasis in the Western Ghats.
}, year = {2024}, journal = {Transactions of The Royal Society of Tropical Medicine and Hygiene}, publisher = {Oxford University Press (OUP)}, issn = {0035-9203, 1878-3503}, doi = {10.1093/trstmh/trae102}, language = {ENG}, }