@article{102342,
  keywords = {Quality of Life, HIV co-infection, Visceral leishmaniasis (VL), WHOQOL-BREF},
  author = {Pund R and Vishwas G and Madhukar M and Pandey K and Dhingra S},
  title = {Assessment of quality of life in visceral leishmaniasis patients coinfected with HIV: a comparative study in Bihar, India},
  abstract = {<p><strong>Background</strong> This study was aimed to evaluates the quality of life using WHOQOL-BREF in VL patients co-infected with HIV in Bihar, India.</p>

<p><strong>Methods</strong> This cross-sectional study enrolled 240 participants: 60 HIV-VL co-infected, 60 HIV, 60 VL and 60 healthy individuals. Socio-demographic data and QOL assessments used the Hindi WHOQOL-BREF questionnaire. The data were compared using the chi-square test, One-Way ANOVA followed by Tukey’s post-hoc Test. Generalised linear regression was performed for analyses of predictors of QOL, as well as the socio-economic status was determined by using the Modifed Kuppuswamy socio-economic Scale 2022.</p>

<p><strong>Results</strong> HIV-VL co-infected patients reported signifcantly lower QOL scores across all domains (physical, psychological, social relationships, and environmental) compared to healthy individuals (p &lt; 0.05). Notably, psychological (12.17±1.17), social relationship (5.90±1.16), and environmental (14.10±1.68) domains were severely impacted in HIV-VL coinfection in contrast to HIV (p&lt;0.05) and VL (p&lt;0.05).</p>

<p><strong>Conclusion</strong> HIV-VL co-infection profoundly afects quality of life, emphasizing the need for targeted interventions addressing psychological, social and environmental well-being. Future research should prioritize strategies improving QOL and assessing long-term treatment efects in HIV-VL co-infection</p>
},
  year = {2025},
  journal = {Journal of Health, Population and Nutrition},
  volume = {44},
  pages = {11},
  publisher = {Springer Science and Business Media LLC},
  issn = {2072-1315},
  url = {https://link.springer.com/article/10.1186/s41043-025-00821-6},
  doi = {10.1186/s41043-025-00821-6},
  language = {eng},
}