@article{102480,
  keywords = {Chronic schistosomiasis, Immunochromatography, Point-of-care diagnostics, schistosomiasis screening, sub-Saharan migrants},
  author = {Hegazy AHA and Pérez-Quílez  O and López-Muñoz I and Chamorro A and  Abad E and San José A and  Valera J and Valerio L and Soldevila L and Gorriz E and Herena D and Fernández-Pedregal E and Llibre JM and Fernández-Rivas G and Joan Cardona P and Vallès X and  Roure S},
  title = {Performance (Sensitivity and Specificity) of a New Point-of-Care Immunochromatography to Screen for Imported Chronic Schistosomiasis Among Long-Term Sub-Saharan Migrants },
  abstract = {<p><strong>Background</strong></p>

<p>Imported schistosomiasis is underdiagnosed among long-term migrants in non-endemic countries. Reference standard tests are lacking for the diagnosis of chronic schistosomiasis.</p>

<p><strong>Methods</strong></p>

<p>This study evaluated the sensitivity and specificity of a new immunochromatography (ICT) test using serum (s) or point-of-care finger-prick (FP) whole blood against standard serological tests in long-term migrants from sub-Saharan Africa.</p>

<p><strong>Results</strong></p>

<p>A total of 202 individuals were screened, with a mean age of 42.7 years. Of these, 75.7% were male, and 42.6% were from Senegal. Test positivity rates were 15.8% for ELISA, 24.3% for ICT-p, 46.5% for ICT-b (s), and 28.7% for ICT-b (FP). All tests showed good agreement with a clinical score but with heterogeneous agreement between them. Our results indicates a higher sensitivity for ICT-b (s). Positive responses after treatment suggest good specificity for all tests.</p>

<p><strong>Conclusions</strong></p>

<p>ICT-b (s) shows a higher sensitivity than the other standard tests. An ICT-b (FP) strategy could be used as a first-step point-of-care screening tool for probable chronic schistosomiasis.</p>
},
  year = {2025},
  journal = {Open Forum Infectious Diseases},
  volume = {12},
  publisher = {Oxford Academic},
  url = {https://academic.oup.com/ofid/article/12/7/ofaf328/8196494#google_vignette},
  language = {eng},
}