@article{102481,
  keywords = {Exercise, Chronic Disease, Health behaviour, sedentary behavior},
  author = {Xavier IGG and Andrade PM and Vitor RDL and Barros TC and Silva WT and Portela LF and Holanda MTD and Sangenis LHC and Silva GMSD and Mazzoli-Rocha F and Mendes FDSNS and Costa ARD and Vieira MC and Almeida DPMD and Valete CM and Hasslocher-Moreno AM and Costa HS and Paravidino VB and Gonçalves TR and Saraiva RM and Mediano MFF},
  title = {Association Between Physical Activity, Sedentary Time, and Quality of Life in Patients with Chagas Disease During COVID-19 Pandemic in Brazil: A Cross-Sectional Study},
  abstract = {<p><strong>Background: </strong>COVID-19 led to social isolation, potentially reducing physical activity (PA), increasing sedentary time, and lowering quality of life (QoL). This study investigated the association between these factors in patients with Chagas disease (ChD) during the pandemic.</p>

<p><strong>Methods:</strong> This cross-sectional study included 187 patients with ChD. PA and sedentary time were assessed by the IPAQ-short and QoL by the WHOQOL-Bref. The relationship between PA levels and sedentary time with QoL were assessed using unadjusted and adjusted generalized linear models.</p>

<p><strong>Results:</strong> The highest tertile of total PA was positively associated with the psychological (Exp β = 1.11; 95% CI: 1.02–1.22) and environmental (Exp β = 1.12; 95% CI: 1.01–1.23) QoL domains. The intermediate (Exp β = 1.12; 95% CI: 1.01–1.25) and highest (Exp β = 1.14; 95% CI: 1.02–1.27) tertiles of moderate-to-vigorous PA were positively associated with the physical domain. Similarly, both the intermediate (Exp β = 1.11; 95% CI: 1.01–1.22) and highest (Exp β = 1.12; 95% CI: 1.01–1.21) tertiles of moderate-to-vigorous PA were positively associated with the psychological domain. The highest tertile of sedentary time was associated with a decrease in the physical domain (Exp β = 0.88; 95% CI: 0.79–0.98).</p>

<p><strong>Conclusions:</strong> Higher levels of total and moderate-to-vigorous PA were associated with better QoL, while greater sedentary time was associated with poorer QoL.</p>
},
  year = {2025},
  journal = {International Journal of Environmental Research and Public Health},
  volume = {22},
  publisher = {MDPI AG},
  issn = {1660-4601},
  url = {https://www.mdpi.com/1660-4601/22/7/1137},
  doi = {10.3390/ijerph22071137},
  language = {eng},
}