@article{103367,
  keywords = {One Health, Developing countries, Implementation science, performance indicators, Systematic review, veterinary services, zoonosis prevention},
  author = {Sahiman K and Azizah S and Kuswati K and Iekram A},
  title = {One health strategies for zoonosis prevention in developing countries: A systematic review (2015-2025).},
  abstract = {<p><strong>BACKGROUND: </strong></p>

<p>Despite growing global investment in One Health initiatives, limited systematic synthesis exists examining veterinary authority strategies and their performance outcomes in developing countries, creating a knowledge gap for evidence-based policy formulation.</p>

<p><strong>OBJECTIVE: </strong></p>

<p>To develop a comprehensive taxonomy of One Health zoonosis prevention strategies implemented by veterinary authorities in developing countries and establish quantitative effectiveness patterns across resource-constrained settings.</p>

<p><strong>METHODS: </strong></p>

<p>We conducted a systematic review following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines, searching Scopus, Web of Science, and PubMed for peer-reviewed studies published between January 2015 and July 2025. Two reviewers independently screened 126 records after deduplication with inter-rater agreement (κ&nbsp;=&nbsp;0.82). We employed mixed-methods synthesis integrating thematic analysis and quantitative effectiveness scoring across 42 included studies.</p>

<p><strong>RESULTS: </strong></p>

<p>From 42 studies spanning 18 countries, we identified 14 distinct One Health strategies organized into three dominant modalities: intersectoral coordination mechanisms (35.7%), surveillance system enhancement (28.6%), and integrated service delivery (21.4%). Integrated approaches consistently demonstrated superior effectiveness scores (77-90, 95% CI: 73-94) compared to single-intervention strategies (25-95, 95% CI: 18-88). Mobile surveillance systems achieved 14-fold reporting increases (RR&nbsp;=&nbsp;14.0, 95% CI: 13.8-14.2), while integrated surveillance systems demonstrated improved epidemiological understanding across human-animal interfaces.</p>

<p><strong>CONCLUSIONS: </strong></p>

<p>Implementation quality and strategic integration represent more critical determinants of success than intervention type or resource intensity alone. Sub-optimal policy implementation and poor inter-sectoral coordination were consistently identified as barriers to achieving desired outcomes. These findings provide evidence-based guidance for optimizing limited resources in developing countries.</p>
},
  year = {2026},
  journal = {Research in veterinary science},
  volume = {203},
  month = {05/2026},
  issn = {1532-2661},
  url = {https://www.sciencedirect.com/science/article/abs/pii/S0034528826000433?via%3Dihub},
  doi = {10.1016/j.rvsc.2026.106091},
  language = {ENG},
}