@article{24702, keywords = {Rifampicin, Buruli ulcer}, author = {Jansson M and Beissner M and Phillips RO and Badziklou K and Piten E and Maman I and Sarfo FS and Huber KL and Rhomberg A and Symank D and Wagner M and Wiedemann FX and Nitschke J and Kere AB and Herbinger K and Adjei O and Löscher T and Bretzel G}, title = {Molecular determination of Rifampicin resistance in clinical samples of patients with buruli ulcer disease: A comparison of two assays.}, abstract = {

This study evaluates a novel assay to detect rifampicin resistance in clinical Mycobacterium ulcerans isolates. Although highly susceptible for PCR inhibitors in 50% of samples tested, the assay was 100% M. ulcerans-specific and yielded >98% analyzable sequences with a lower limit of detection of 100-200 copies of the target sequence.

}, year = {2014}, journal = {Journal of clinical microbiology}, month = {2014 Jan 29}, issn = {1098-660X}, url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3993512/pdf/zjm1246.pdf}, doi = {10.1128/JCM.03119-13}, language = {eng}, }