@article{26949, keywords = {Young Adult, uganda, Time Factors, Socioeconomic Factors, onchocerciasis, Nigeria, Medication adherence, Male, Ivermectin, Humans, Female, Endemic Diseases, Drug Administration Schedule, Child, Cameroon, Antiparasitic Agents, Adult, Adolescent}, author = {Amazigo U and Wanji S and Ndyomugyenyi R and Elhassan E and Brieger W and Okeibunor J and Abiose A}, title = {Characteristics of persons who complied with and failed to comply with annual ivermectin treatment.}, abstract = {

OBJECTIVE: To assess individual compliance with annual ivermectin treatment in onchocerciasis-endemic villages.

METHODS: Multi-site study in eight APOC-sponsored projects in Cameroon, Nigeria and Uganda to identify the socio-demographic correlates of compliance with ivermectin treatment. A structured questionnaire was administered on 2305 persons aged 10 years and above. Two categories of respondents were purposively selected to obtain both high and low compliers: people who took ivermectin 6-8 times and 0-2 times previously. Simple descriptive statistics were employed in characterizing the respondents into high and low compliers, while some socio-demographic and key perceptual factors were employed in regression models constructed to explain levels of compliance among the respondents.

RESULTS: Some demographic and perceptual factors associated with compliance were identified. Compliance was more common among men (54.4%) (P < 0.001). Adults (54.6%) had greater rates of high compliance (P < 0.001. The mean age of high compliers (41.5 years) was significantly older (35.8 years) (t = 8.46, P < 0.001). Perception of onchocerciasis and effectiveness of ivermectin influenced compliance. 81.4% of respondents saw benefits in annual ivermectin treatment, high compliance among those who saw benefits was 59.3% compared to 13.3% of those who did not (P < 0.001).

CONCLUSION: Efforts to increase compliance with ivermectin treatment should focus on providing health education to youth and women. Health education should also highlight the benefits of taking ivermectin.

}, year = {2012}, journal = {Tropical medicine & international health : TM & IH}, volume = {17}, pages = {920-30}, issn = {1365-3156}, doi = {10.1111/j.1365-3156.2012.03007.x}, note = {

 

 

 

}, language = {eng}, }