@article{27893, keywords = {Neglected tropical diseases (NTDs), Leishmaniasis, Treatment, Capacity building, Africa}, author = {Wasunna M and Musa A and Hailu A and Khalil EA G and Olobo J and Juma R and Wells S and Alvar J and Balasegaram M}, title = {The Leishmaniasis East Africa Platform (LEAP): strengthening clinical trial capacity in resource-limited countries to deliver new treatments for visceral leishmaniasis.}, abstract = {

Visceral leishmaniasis is a neglected tropical disease endemic in East Africa where improved patient-adapted treatments are needed. The Leishmaniasis East Africa Platform (LEAP) was created in 2003 to strengthen clinical research capacity, serve as a base for training, and evaluate and facilitate implementation of new treatments. Major infrastructure upgrades and personnel training have been carried out. A short course of Sodium Stibogluconate and Paramomycin (SSG&PM) was evaluated and is now first-line treatment in the region; alternative treatments have also been assessed. LEAP can serve as a successful model of collaboration between different partners and countries when conducting clinical research in endemic countries to international standards.

}, year = {2016}, journal = {Transactions of the Royal Society of Tropical Medicine and Hygiene}, issn = {1878-3503}, url = {http://trstmh.oxfordjournals.org/content/early/2016/06/07/trstmh.trw031.full.pdf+html}, doi = {10.1093/trstmh/trw031}, language = {eng}, }