@article{28100, keywords = {Trachoma, India, Eyes, Cornea, Blindness Chlamydia trachomatis}, author = {Malhotra S and Vashist P and Gupta N and Kalaivani M and Satpathy G and Shah A and Krishnan S and Azad R}, title = {Prevalence of trachoma in Car-Nicobar Island, India after three annual rounds of mass drug administration with azithromycin.}, abstract = {

BACKGROUND: A high proportion of active trachoma infection in children of Car-Nicobar Island was reported through the Trachoma Rapid Assessment survey conducted in year 2010 by the same researchers. Annual mass drug treatment with azithromycin was administered from years 2010-12 to all individuals residing in this island for reducing the burden of active trachoma infection. A cross-sectional prevalence survey was conducted in the year 2013 to assess the post-treatment burden of trachoma in this population.

METHODS: In the 15 randomly selected compact segments from each village of the island, children aged 1-9 years were examined for evidence of active trachoma infection and participants aged ten years and above were examined for trachomatous trichiasis and corneal opacity.

RESULTS: A total of 809 children (1-9 years) and 2735 adults were examined. Coverage with azithromycin for all the three rounds was more than 80%. The prevalence of active trachoma infection in children aged 1-9 years old was 6.8% (95% CI 5.1, 8.5) and Trachomatous Trichiasis (TT) was 3.9% (95% CI 3.2, 4.6). The risk factors associated with active trachoma infection were older age and unclean faces. The risk factors associated with TT were older age and lower literacy level.

CONCLUSION: Trachoma has not been eliminated from Car-Nicobar Island in accordance to 'Global Elimination of Trachoma, 2020' guidelines. Sustained efforts and continuous surveillance admixed with adequate programmatic response is imperative for elimination of trachoma in the island.

}, year = {2016}, journal = {PloS one}, volume = {11}, pages = {e0158625}, issn = {1932-6203}, url = {http://journals.plos.org/plosone/article/asset?id=10.1371%2Fjournal.pone.0158625.PDF}, doi = {10.1371/journal.pone.0158625}, language = {eng}, }