@article{94102,
  keywords = {Immunology and Allergy, Infectious Diseases, Sampling, Control programmes},
  author = {Coffeng L and Malizia V and Vegvari C and Cools P and Halliday KE and Levecke B and Mekonnen Z and Gichuki PM and Sayasone S and Sarkar R and Shaali A and Vlaminck J and Anderson RM and de Vlas S},
  title = {Impact of Different Sampling Schemes for Decision Making in Soil-Transmitted Helminthiasis Control Programs},
  abstract = {<jats:title>Abstract</jats:title>
               <jats:p>Starting and stopping preventive chemotherapy (PC) for soil-transmitted helminthiasis is typically based on the prevalence of infection as measured by Kato-Katz (KK) fecal smears. Kato-Katz-based egg counts can vary highly over repeated stool samples and smears. Consequentially, the sensitivity of KK-based surveys depends on the number of stool samples per person and the number of smears per sample. Given finite resources, collecting multiple samples and/or smears means screening fewer individuals, thereby lowering the statistical precision of prevalence estimates. Using population-level data from various epidemiological settings, we assessed the performance of different sampling schemes executed within the confines of the same budget. We recommend the use of single-slide KK for determining prevalence of moderate-to-heavy intensity infection and policy decisions for starting and continuing PC; more sensitive sampling schemes may be required for policy decisions involving stopping PC. Our findings highlight that guidelines should include specific guidance on sampling schemes.</jats:p>},
  year = {2019},
  journal = {The Journal of Infectious Diseases},
  volume = {221},
  pages = {S531-S538},
  publisher = {Oxford University Press (OUP)},
  issn = {0022-1899, 1537-6613},
  url = {https://watermark.silverchair.com/jiz535.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAqgwggKkBgkqhkiG9w0BBwagggKVMIICkQIBADCCAooGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMOkPv6vNVM9crjZUJAgEQgIICW4Z6vqzWK7GrPaF58ccd4ZHlLhOV1MWGi6EB3TE4YBk6gUil},
  doi = {10.1093/infdis/jiz535},
  language = {eng},
}