@article{95025,
  keywords = {General Medicine, Wound care},
  author = {Kim KJ and Min JH and Yoo I and Kim SW and Lee J and Ryu S and You YH and Park JS and Jeong WJ and Cho YC and Oh SK and In YN and Ahn HJ and Kang CS and Kyung H and Lee BK and Lee DH and Lee DH},
  title = {Negative pressure wound therapy for skin necrosis prevention after snakebite in the emergency department},
  abstract = {This retrospective cohort study aimed to compare the effectiveness of conventional treatment and ultra-early application of negative pressure wound therapy (NPWT) in patients with snakebites.

Patients who visited the emergency department within 24 hours after a snakebite were assigned to the non- NPWT or NPWT group. Swelling resolution time and rates of necrosis, infection, and operations were compared between the 2 groups. The Stony Brook Scar Evaluation Scale was used to measure short- and long-term wound healing results.

Among the included 61 patients, the swelling resolution time was significantly shorter in the NPWT group than in non- NPWT group (P = .010). The NPWT group showed lower necrosis (4.3% versus 36.8%; P = .003) and infection (13.2% and 4.3%; P = .258) rates than the non- NPWT group. The median Stony Brook Scar Evaluation Scale scores were higher in the NPWT group than in the non- NPWT group (P< .001).

These findings suggest that ultra-early application of NPWT reduces edema, promotes wound healing, and prevents necrosis in patients with snakebites.},
  year = {2021},
  journal = {Medicine},
  volume = {100},
  pages = {e24290},
  publisher = {Ovid Technologies (Wolters Kluwer Health)},
  issn = {0025-7974, 1536-5964},
  url = {https://journals.lww.com/md-journal/Fulltext/2021/01220/Negative_pressure_wound_therapy_for_skin_necrosis.135.aspx},
  doi = {10.1097/md.0000000000024290},
  language = {eng},
}