@article{95027, keywords = {Microbiology (medical), Infectious Diseases, General Medicine}, author = {Lim W and Eadie K and Konings M and van de Sande W}, title = {MycetOS – An open research model discover new drugs to treat one of the most neglected disease – Mycetoma}, abstract = {Mycetoma, a neglected tropical disease, is a chronic granulomatous subcutaneous infection caused by bacteria(actinomycetoma) and fungi(eumycetoma). MycetOS is an ongoing community-driven, open-source-drug-discovery programme aiming to discover new drugs that can treat eumycetoma. Currently, Itraconazole is the only option available, yet, treatment takes years and 25% of patients have recurrences. Amputation of the affected limbs are common and is a huge socio-economic burden for patients in tropical and sub-saharan countries. There is an urgent need to discover new drugs to treat eumycetoma.}, year = {2020}, journal = {International Journal of Infectious Diseases}, volume = {101}, pages = {388}, publisher = {Elsevier BV}, issn = {1201-9712}, url = {https://www.ijidonline.com/action/showPdf?pii=S1201-9712%2820%2931735-5}, doi = {10.1016/j.ijid.2020.09.1018}, language = {eng}, }