@article{96367,
  keywords = {albendazole (ALB)},
  author = {Pion S and Chesnais C and Weil G and Louya F and Boussinesq M and Missamou F},
  title = {Impact of Semi-Annual Albendazole on Lymphatic Filariasis and Soil-Transmitted Helminth Infection: Parasitological Assessment after 14 Rounds of Community Treatment.},
  abstract = {<p>Between October 2012 and October 2015, we conducted a community trial to assess the impact of semi-annual (twice yearly) community treatment with albendazole on lymphatic filariasis in Seke Pembe, a village in the Republic of the Congo. Semi-annual community treatment with albendazole has been continued in the community since October 2015. We conducted an additional parasitological assessment survey in October 2019, 6 months after the 14th round of semi-annual treatment. Between October 2012 and October 2015, Wuchereria bancrofti antigenemia and microfilaremia rates in the community had decreased from 17.3% to 4.7% and from 5.3% to 0.3%, respectively. In October 2019, the antigenemia rate had decreased further to 2.8% (19 of 687). No microfilariae were found in night blood smears from persons with circulating filarial antigenemia (0 of 16), suggesting that W. bancrofti transmission has been interrupted in Seke Pembe. Semi-annual albendazole treatments also reduced significantly infection rates with soil-transmitted helminths.</p>
},
  year = {2021},
  journal = {The American journal of tropical medicine and hygiene},
  month = {12/2021},
  issn = {1476-1645},
  url = {https://www.ajtmh.org/downloadpdf/journals/tpmd/aop/article-10.4269-ajtmh.21-0731/article-10.4269-ajtmh.21-0731.xml},
  doi = {10.4269/ajtmh.21-0731},
  language = {eng},
}