@article{97123,
  keywords = {Antivenom, clinical practice guideline, Health Education, snakebite, Validation},
  author = {Rocha G and Farias A and Alcântara J and Machado V and Murta F and Val F and Cristino J and Santos A and Ferreira M and Marques L and Rocha Y and Sachett A and Almeida M and Alencar A and Brasileiro L and Carvalho É and Bisneto P and Lacerda M and Tupetz A and Staton C and Vissoci J and Teixeira E and Gerardo C and Wen F and Sachett J and Monteiro W},
  title = {Validation of a Culturally Relevant Snakebite Envenomation Clinical Practice Guideline in Brazil.},
  abstract = {<p>Snakebite envenoming (SBE) is a neglected tropical disease with significant global morbidity and mortality. Even when antivenom is available in low-resource areas, health workers do not receive adequate training to manage SBEs. This study aims to develop and validate a clinical practice guideline (CPG) for SBE management across Brazil. A panel of expert judges with academic and/or technical expertise in SBE management performed content validation. The content validity index (CVI) score was 90% for CPG objectives, 89% for structure and presentation and 92% for relevance and classified the CPG as valid. A semantic validation was performed by analyzing focus group discussions with doctors and nurses from three municipalities of the Brazilian Amazon, after a 5-day meeting during which the CPG was presented. Two central themes emerged: knowledge acquired during the meeting and recommendations for improving the CPG. Based on these results, the CPG was revised into a final version. This study presents the successful development and validation process of a CPG for SBE management, which is targeted to a specific low-resource, high-burden setting. This development and validation process can be adapted to other settings and/or other neglected tropical diseases.</p>
},
  year = {2022},
  journal = {Toxins},
  volume = {14},
  month = {05/2022},
  issn = {2072-6651},
  url = {https://www.mdpi.com/2072-6651/14/6/376/pdf?version=1653811110},
  doi = {10.3390/toxins14060376},
  language = {eng},
}