@article{98915, keywords = {Infectious Diseases, Parasitology}, author = {Lim RM and Arme TM and Pedersen AB and Webster JP and Lamberton PH}, title = {Defining schistosomiasis hotspots based on literature and shareholder interviews}, abstract = {
The World Health Organization (WHO) recently proposed a new operational definition which designates communities with ≥10% prevalence of Schistosoma spp. infection as a persistent hotspot, when, after at least two rounds of high-coverage annual preventive chemotherapy, there is a lack of appropriate reduction. However, inconsistencies and challenges from both biological and operational perspectives remain, making the prescriptive use of this definition difficult. Here, we present a comprehensive analysis of the use of the term ‘hotspot’ across schistosomiasis research over time, including both literature searches and opinions from a range of stakeholders, to assess the utility and generalisability of the new WHO definition of a persistent hotspot. Importantly, we propose an updated definition based on our analyses.
}, year = {2023}, journal = {Trends in Parasitology}, pages = {1-18}, publisher = {Elsevier BV}, issn = {1471-4922}, url = {https://www.cell.com/action/showPdf?pii=S1471-4922%2823%2900227-1}, doi = {10.1016/j.pt.2023.09.006}, language = {Eng}, }