02658nas a2200469 4500000000100000008004100001260001600042653002500058653001400083653003500097100001600132700001200148700001500160700001400175700001400189700001500203700002200218700001300240700001600253700001600269700002000285700001300305700001400318700001400332700002000346700002000366700001500386700001600401700002100417700001500438700001400453700001600467700001600483700001200499700001900511700001200530245010000542300001400642490000700656520151100663022001402174 2024 d bElsevier BV10aTerminology as Topic10aConsensus10aimported human schistosomiasis1 aTamarozzi F1 aMazzi C1 aAntinori S1 aArsuaga M1 aBecker SL1 aBottieau E1 aCamprubi-Ferrer D1 aCaumes E1 aDuvignaud A1 aGrobusch MP1 aJaureguiberry S1 aJordan S1 aMueller A1 aNeumayr A1 aPerez-Molina JA1 aSalas-Coronas J1 aSalvador F1 aTomasoni LR1 avan Hellemond JJ1 aVaughan SD1 aWammes LJ1 aZammarchi L1 aBuonfrate D1 aHuits R1 aVan Lieshout L1 aGobbi F00aConsensus definitions in imported human schistosomiasis: a GeoSentinel and TropNet Delphi study ae627-e6370 v243 a
Terminology in schistosomiasis is not harmonised, generating misunderstanding in data interpretation and clinical descriptions. This study aimed to achieve consensus on definitions of clinical aspects of schistosomiasis in migrants and returning travellers. We applied the Delphi method. Experts from institutions affiliated with GeoSentinel and TropNet, identified through clinical and scientific criteria, were invited to participate. Five external reviewers revised and pilot-tested the statements. Statements focusing on the definitions of acute or chronic; possible, probable, or confirmed; active; and complicated schistosomiasis were managed through REDCap and replies managed in a blinded manner. Round 1 mapped the definitions used by experts; subsequent rounds were done to reach consensus, or quantify disagreement, on the proposed statements. Data were analysed with percentages, medians, and IQRs of a 5-point Likert scale. The study was terminated on the basis of consensus or stability-related and time-related criteria. 28 clinicians and scientists met the criteria for experts. 25 (89%) of 28 experts replied to Round 1, 18 (64%) of 28 to Round 2, 19 (68%) of 28 to Round 3, and 21 (75%) of 28 to at least two rounds. High-level consensus (79–100% agreement and IQRs ≤1) was reached for all definitions. Consensus definitions will foster harmonised scientific and clinical communication and support future research and development of management guidelines for schistosomiasis.
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