02733nas a2200289 4500000000100000008004100001260004400042653002700086653001600113653002700129653001400156653002400170653002700194653002200221653001800243100001400261700001000275700001300285700001200298700001000310700001300320245018200333856009400515300000800609520181200617022001402429 2024 d bSpringer Science and Business Media LLC10aAdverse drug reactions10aAlbendazole10aAttitude, and practice10aKnowledge10aMass administration10anational deworming day10aPharmacovigilance10aSensitization1 aSheoran B1 aDeb T1 aTuteja M1 aKumar A1 aDas A1 aSharma N00aImpact of Sensitization on School Teachers' Knowledge and Attitudes Towards Adverse Drug Reaction Reporting During National Deworming Day: A Prospective Quasi-Experimental Study uhttps://assets.cureus.com/uploads/original_article/pdf/308168/20241107-1510322-xqqgfv.pdf a1-93 a

Background: School teachers play a crucial role in executing administration of single dose albendazole to school children on National Deworming Day (NDD). Effective reporting of adverse drug reactions (ADRs) during such mass administration of medicines at the time of such public health programmes is vital for several policy decisions on safety. The study aims to evaluate teachers' knowledge and attitudes on ADR reporting regarding NDD and assess the impact of a sensitization program.

Method: A total of 163 school teachers from 94 schools in the district, who gave informed consent were included. The study utilized a pretested and prevalidated questionnaire, scored on a 0-10 scoring scale. Employing a prospective quasi-experimental one-group pre-test and post-test research design, the primary aim was to evaluate the impact of the awareness program, with secondary objectives focused on demographic correlations with program effectiveness.

Results: The study shows a significant improvement in participants' scores from the pre-test (mean score of 5.60) to the post-test (mean score of 8.28), resulting in a mean deviation of -2.68±1.74 (p < .001), suggesting that the intervention significantly enhanced outcomes. Additionally, the results indicate that the mean posttest score was slightly higher among urban participants in comparison to rural participants, with mean scores of 8.45 and 8.10, respectively.

Conclusion: The sensitization program significantly improved the knowledge and attitude of school teachers engaged in NDD regarding ADR reporting. However, long-term studies on the impact of this improvement in knowledge and attitude on actual ADR reporting need to be planned.

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