02271nas a2200217   4500000000100000008004100001260001600042653002500058653002400083653002500107100002500132700001500157700001800172700002300190700002700213700001600240245010500256300000700361520167100368022001402039       2025                            d  bElsevier BV10aSnakebite envenoming10aSnakebite diagnosis10aTreatment strategies1 aBrilhante-da-Silva N1 aRoberto SA1 aReis Prado ND1 aMachado Marinho AC1 aCeledonio Fernandes CF1 aPereira SDS00aDiagnostic platforms for snakebite: current approaches and challenges in medically important species  a243 a<p>Diagnosing snakebite envenoming is a critical aspect of managing this life-threatening condition. Achieving the impacts and clinical applications of the diagnosis of snakebites is important to help clarify the challenges faced in identifying venomous snakebites and implementing effective treatment strategies. The complexity of the envenomation requires a comprehensive diagnostic approach, considering both clinical symptoms and laboratory findings. Despite advances in diagnostic technologies, the lack of standardized tools represents a significant obstacle to obtaining accurate and timely assessments. This paper analyzes the state-of-the-art snakebite diagnosis, emphasizing the need for methodologies for differential diagnosis of snakebites. Furthermore, it investigates the far-reaching consequences of late or incorrect diagnoses, emphasizing their role in the potential development of serious morbidity and even mortality. The discussion extends to the global health burden caused by snakebite envenoming, emphasizing the importance of personalized diagnostic methods in regions with diverse snake species. Furthermore, the review explores recent advances in the global scale diagnosis of snakebite venom. The clinical applications of these innovations are explored, highlighting their potential to revolutionize snakebite management in resource-limited settings. By addressing the multifaceted challenges in snakebite diagnosis, this summary contributes to ongoing efforts to mitigate the global impact of snakebite envenoming by highlighting the critical need for collaborative research, standardization, and accessibility of diagnostic tools.</p>
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