02012nas a2200361   4500000000100000008004100001260003700042653000900079100001200088700001500100700001300115700002000128700001100148700001500159700001400174700001400188700001400202700001400216700001500230700001600245700001500261700001200276700001500288700001500303700001600318700001400334245003800348856009900386300001300485490000700498520113100505022001401636       2025                            d  bPublic Library of Science (PLoS)10aNoma1 aGalli A1 aComparet M1 aDagne DA1 aBaratti-Mayer D1 aCao TH1 aGuérin PJ1 aGuevara M1 aHetzel MW1 aJeantet C1 aMpinga EK1 aMuendane V1 aOkanlawon M1 aPlacella E1 aRibes M1 aSherlock M1 aUtzinger J1 aSteinmann P1 aVinetz JM00aDefining the noma research agenda  uhttps://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0012940&type=printable  ae00129400 v193 a<p>• A 1-day symposium brought together over 100 individuals with lived experience of noma, expertise in neglected tropical diseases, and public health, including researchers, health advocates, and clinicians. The involvement of noma survivors was invaluable and added an important perspective in defining the research agenda.</p>

<p>• The most pressing research needs identified were: ○ Clear case definition of noma ○ Early case detection and robust surveillance ○ Psychosocial and economic impact of noma ○ Decision support for diagnosing acute necrotizing gingivitis and associated antibiotic regimen(s) with treatment duration ○ Deeper understanding of risk factors and social determinants ○ Identification of effective information, education, and communication strategies ○ Effectiveness of surgical services ○ Testing decentralized follow-up for patients • An important conclusion was that noma research and control activities must be integrated across sectors and disciplines, such as neglected tropical diseases, oral health, nutrition, and child health programs including immunization.</p>
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