02334nas a2200409   4500000000100000008004100001260004400042653001400086653002500100653001400125653001400139653001300153100001500166700001400181700001200195700001100207700001100218700001400229700001400243700001500257700001500272700001300287700001400300700001400314700001300328700001200341700001600353700001200369700001100381700001400392245015000406856008500556300000600641490000700647520125600654022001401910       2025                            d  bSpringer Science and Business Media LLC10aDeworming10aIntestinal parasites10aInfection10aPregnancy10aEthiopia1 aYibeltal K1 aWorkneh F1 aFasil N1 aBaye E1 aKang Y1 aKidane WT1 aTsegaye S1 aBerhane YY1 aHaymanot B1 aOlson IE1 aDerebe MM1 aMolina RL1 aWylie BJ1 aChan GJ1 aChristian P1 aWorku A1 aLee AC1 aBerhane Y00aA single presumptive deworming may not suffice to reduce the burden of intestinal parasitic infections during pregnancy in rural Amhara, Ethiopia  uhttps://bmcresnotes.biomedcentral.com/articles/10.1186/s13104-025-07309-w#citeas  a50 v183 a<p><strong>Objective</strong> This study aimed to assess the prevalence of intestinal parasitic infections among pregnant women in the third trimester who received prior presumptive deworming in 12 health centers in the Amhara region, Ethiopia. This sub-study was part of the parent Enhancing Nutrition and Antenatal Infection Treatment (ENAT) study; a randomized clinical effectiveness study conducted to determine the effectiveness of packages of antenatal interventions to enhance maternal nutrition and infection management on birth outcomes.</p>

<p><strong>Results</strong> Three hundred fifty women provided a stool sample in their 3rd trimester for screening using wet mount microscopy. All women had previously received 500&nbsp;mg of presumptive mebendazole in the 2nd trimester. One in three women (109/350, 31.0%) were found to have a parasitic stool infection after prior deworming and 15% of women reported gastrointestinal symptoms. The most common infections were Giardia lamblia (n = 43, 37.4%), Entamoeba histolytica (n = 40, 34.8%), and Hookworm (n = 25, 21.7%). Six mothers had co-infections with at least two parasites with trophozoites of Giardia lamblia and Entamoeba histolytica co-infection being dominant.</p>
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