02614nas a2200349   4500000000100000008004100001260001600042653002100058653001600079653001500095653001100110653001300121653002400134100001300158700001600171700001600187700001700203700001600220700001400236700001200250700001400262700001200276700001500288700001300303700001400316245018500330856026000515300000700775490000700782520146100789022001402250       2024                            d  bElsevier BV10aSchistosomiasis 10aCommunities10aValidation10aUganda10aDistrict10aImplementation unit1 aAdriko M1 aTinkitina B1 aArinaitwe M1 aTukahebwa EM1 aMubangizi A1 aOrtega JC1 aZoure H1 aMwinzi PN1 aKinvi B1 aDjirmay AG1 aNjenga S1 aMazigo HD00aTime to change implementation units for mass drug administration against schistosomiasis in Uganda: Evidence from Communities levels data validation and its implication in planning  uhttps://pdf.sciencedirectassets.com/313542/1-s2.0-S2405673124X00045/1-s2.0-S2405673124000588/main.pdf?X-Amz-Security-Token=IQoJb3JpZ2luX2VjEP%2F%2F%2F%2F%2F%2F%2F%2F%2F%2F%2FwEaCXVzLWVhc3QtMSJGMEQCIAVNoaiO9z50ZUp%2F2IxCqa0C%2FWUJ59m9rtSNjXy13iWCAiBJgrJmih  a130 v273 a<p>Uganda started implementing mass drug administration against schistosomiasis in 2003, with district used as an implementation unit. This resulted into misclassification of communities into wrong risk levels, under-or-over treatment and over request of praziquantel (PZQ) drugs. The objective of the current study was to reviewing the community data available at World Health Organization/ESPEN database to understand the status of schistosomiasis and identify pockets with infection. The decision tree assessment tool was used to analyzed schistosomiasis epidemiological data of 7501 communities. Before validation, the schistosomiasis endemicity status of 79&nbsp;% of communities was not known. After validation, 58.6&nbsp;%, 22.6&nbsp;% and 16.3&nbsp;% of communities were not endemic, had low and moderate endemicity status. Of 2362 communities classified having high endemicity using a district as implementation unit, 41.6&nbsp;%, 12.7&nbsp;% and 17.3&nbsp;% of them were not endemic, had low and moderate endemicity, while only 22.7&nbsp;% had high endemicity. Using the new treatment guidelines, 2,875,006 school aged children were adequately treated, 18,235 were under-treated and 2,250,013 were over treated. The results show a considerable change in endemicity status when communities were used as an implementation unit compared to district. Thus, the country control programme is recommended to use communities as implementation unit.</p>
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