02385nas a2200253 4500000000100000008004100001260001600042653003300058653001200091653001900103653002900122100001600151700001500167700001300182700001300195700002200208700001800230700001200248700001300260245011100273856007200384520166100456022001402117 2025 d bElsevier BV10aCutaneous Leishmaniasis (CL)10aMorocco10aAtypical forms10aEpidemioclinical profile1 aChekairi FE1 aMouhsine Z1 aBaghad B1 aBaline K1 aEl Idrissi Saik I1 aAbdellaoui MS1 aRiyad M1 aChiheb S00aAtypical presentations of cutaneous leishmaniasis in Morocco: Emerging clinical and epidemiological trends uhttps://www.sciencedirect.com/science/article/pii/S22142509250017873 a

Background

Cutaneous leishmaniasis (CL) is an endemic parasitic disease in Morocco that exhibits an increasing diversity of clinical manifestations. This clinical polymorphism often leads to misdiagnosis and delays in treatment. The aim of our study was to illustrate the atypical presentations of CL through a series of six cases diagnosed in our department, highlighting the diagnostic challenges and public health implications.

Case presentations

We report six atypical cases of CL. Case 1: a 33-year-old male with an ulcerative and crusty lesion on the lower lip mucosa, mimicking epidermoid carcinoma. Case 2: a 44-year-old male with a chondritis-like erythematosquamous plaque on the left ear. Case 3: a 25-year-old male with a well-limited erosive plaque on the right arm, developed leishmaniasis recidivans. Case 4: a 53-year-old female with ulcero-verrucous facial lesions and concomitant cutaneous lupus. Case 5: a 69-year-old female with sarcoidosis-like papulo-nodular facial lesions and an infiltrated nasal plaque mimicking lupus pernio. Case 6: a 75-year-old female with a crateriform lesion on the nose suggestive of keratoacanthoma.

Conclusion

These cases illustrate the changing clinical and epidemiological profile of CL in Morocco, highlighting the importance of early recognition and precise diagnosis through detailed anamnesis and parasitological examinations. It underlines the necessity for enhanced epidemiological surveillance and awareness-raising among practitioners to improve the management and control of the disease.

 a2214-2509