01858nas a2200181   4500000000100000008004100001260001600042653002600058653003700084100001200121700002300133700001500156700001300171245010300184856011400287520126100401022001401662       2025                            d  bElsevier BV10apandemic preparedness10aGlobal Pandemic Risk Observatory1 aDzau VJ1 aGrabar-Kitarovic K1 aPhumpahi J1 aBriand S00aUnifying forces to strengthen pandemic preparedness: a call for a Global Pandemic Risk Observatory  uhttps://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01489-8/abstract?dgcid=raven_jbs_aip_email3 a<p>The COVID-19 pandemic revealed how ill-prepared the world was to detect and respond to global health threats. With over 7·1 million lives lost,<a aria-label="Reference 1" href="https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01489-8/abstract?dgcid=raven_jbs_aip_email#"><sup>1</sup></a>&nbsp;more than US$4·7 trillion in economic damage,<a aria-label="Reference 2" href="https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01489-8/abstract?dgcid=raven_jbs_aip_email#"><sup>2</sup></a>&nbsp;profound disruptions to education and livelihoods, and impacts on mental health, the pandemic exposed weak response capacities and the absence of effective systems to anticipate risk. As countries continue to face pandemic-related aftershocks—rising debt, interrupted human capital, and growing geopolitical instability—threats from climate change, conflict, and technological disruption are only accelerating. The world must be prepared for and prevent future pandemics. Central to achieving these goals is effective monitoring and assessment of pandemic risks. Without the ability to monitor emerging risks in real time, countries will remain vulnerable to future shocks, no matter how much is invested in response.</p>
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