01700nas a2200265   4500000000100000008004100001260001200042653001600054653001800070653002900088653003900117653002400156653003300180653003000213100001200243700001100255700001300266700001200279245013400291856007000425300000800495490000600503520091100509022001401420       2025                            d  c07/202510aIntegration10aMainstreaming10aMass drug administration10aNeglected tropical diseases (NTDs)10aPrimary Health Care10astrengthening health systems10aUniversal health coverage1 aDowns P1 aTate A1 aHarvey D1 aBaker M00aThe changing neglected tropical disease landscape in Africa: implications for policy, practice, and strengthening health systems.  uhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12311265/pdf/qxaf136.pdf  a1-40 v33 a<p><strong>Introduction</strong></p>

<p>Mass drug administration (MDA) has reached up to 1 billion people annually to combat neglected tropical diseases (NTDs). This study explores the evolving NTD landscape in Africa amid shifting disease patterns, funding cuts, and universal health coverage goals.</p>

<p><strong>Methods</strong></p>

<p>We analyzed data from ESPEN and Sightsavers databases to assess historical trends and forecast future treatment needs.</p>

<p><strong>Results</strong></p>

<p>By 2027, few or no MDAs for lymphatic filariasis and trachoma will be required and MDAs for onchocerciasis dropped sharply after 2024. In contrast, schistosomiasis and soil-transmitted helminths continue to require widespread MDA.</p>

<p><strong>Conclusion</strong></p>

<p>To secure elimination gains, remaining MDAs must be completed and broader health systems approaches adopted.</p>
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