01642nas a2200277   4500000000100000008004100001260001200042653002000054653002700074653004000101100001200141700001500153700001300168700001200181700001300193700001200206700001700218700001500235700001300250245009500263856009200358300000800450490000700458520088500465022001401350       2025                            d  c01/202510aChagas' disease10aRapid diagnostic tests10aEquity in access to health services1 aLange K1 aMarchiol A1 aHerazo R1 aMenes M1 aMonroy C1 aRodas A1 aAlcántara B1 aCarrillo K1 aPinazo M00aPerformance evaluation of rapid diagnostic tests for Chagas disease in Jutiapa, Guatemala.  uhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12479034/pdf/1678-9849-rsbmt-58-e0065-2025.pdf  a1-50 v583 a<p><strong>Background</strong></p>

<p>Chagas disease remains a public health problem in Guatemala, with ongoing transmission, both regionally and globally. Diagnosis is complex and often inaccessible. This study evaluated the performance of rapid diagnostic tests for Trypanosoma cruzi infection in Jutiapa.</p>

<p><strong>Methods</strong></p>

<p>Three rapid tests were performed, and the results were compared with those of a diagnostic algorithm for chronic infection.</p>

<p><strong>Results</strong></p>

<p>Although all tests had high specificity, their sensitivities were suboptimal. The combined use of RDTs (Rapid Diagnostic Tests) slightly improved the sensitivity, but it remained below the ideal thresholds.</p>

<p><strong>Conclusions</strong></p>

<p>Further evaluation of RDTs is necessary to enhance access and simplify diagnostic algorithms.</p>
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