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In 2025, the WHO Global Neglected Tropical Diseases Programme marks 20 years of action and data. Since its establishment in 2005, a concerted effort involving pharmaceutical manufacturers, development partners, philanthropic organizations, national health authorities and WHO has contributed to a measurable decline in the global burden of neglected tropical diseases (NTDs).

This report presents progress made in 2023–2024 towards the 2030 targets set in Ending the neglect to attain the Sustainable Development Goals: a road map for neglected tropical diseases 2021-2030 (the road map), including several important analytical updates: