01730nas a2200253   4500000000100000008004100001260004400042653002500086653002900111653001400140653003700154653001700191653001500208100002100223700001400244700001900258700002100277245013600298856008700434300000800521490000700529520092600536022001401462       2025                            d  bSpringer Science and Business Media LLC10aWuchereria bancrofti10aMolecular Xenomonitoring10aAnopheles10aLymphatic filariasis elimination10aBurkina Faso10aOne Health1 aRattanapitoon SK1 aArunsan P1 aThanchonnang C1 aRattanapitoon NK00aMolecular xenomonitoring highlights post-MDA surveillance priorities for sustained Wuchereria bancrofti elimination in Burkina Faso  uhttps://tropmedhealth.biomedcentral.com/counter/pdf/10.1186/s41182-025-00826-1.pdf  a1-20 v533 a<p>The study by Nikièma et al. demonstrates the absence of Wuchereria bancrofti infection in Anopheles mosquitoes a decade after cessation of mass drug administration (MDA) in Burkina Faso. This rare longitudinal evidence underscores the utility of molecular xenomonitoring (MX) as a sensitive early-warning tool that complements traditional transmission assessment surveys (TAS). MX enables detection of recrudescence earlier than human-based diagnostics, particularly in low-prevalence settings, and offers opportunities for integration with malaria vector surveillance. Ethical and operational challenges associated with human landing catches highlight the need for alternative trapping methods to maintain MX sensitivity safely. Sustaining lymphatic filariasis elimination globally will depend on institutionalizing MX alongside TAS, ensuring robust surveillance, and safeguarding long-term programmatic gains.</p>
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