02049nas a2200253   4500000000100000008004100001653003900042653001800081653001900099653001100118653003000129653000900159100003000168700001700198700001800215700001900233700002400252700002300276700002500299245005300324856010700377300000800484520130300492       2025                            d10aNeglected tropical diseases (NTDs)10aGlobal burden10aPublic health 10aPolicy10aUniversal health coverage10aWASH1 aPatel, Sandip Ganpatbhai 1 aModi, Mahir 1 aDarji, Kavya 1 aDarji, Saumil 1 a Jyotsna, Yerrolla 1 aSubbaiah, Pradeep 1 aTiwari, Heena Dixit 00aNeglected Tropical Diseases: A Systematic Review  uhttps://journals.lww.com/jpbs/fulltext/9900/neglected_tropical_diseases__a_systematic_review.1265.aspx  a1-33 a<p>Neglected Tropical Diseases (NTDs) affect over a billion people globally, primarily in low- and middle-income countries. These diseases contribute significantly to morbidity, disability, and poverty, yet receive inadequate attention in global health policies and funding frameworks. A systematic literature search was conducted in PubMed, Scopus, and Web of Science for studies published between 2018 and 2024. Inclusion criteria comprised original research, policy reviews, and global reports on WHO-recognized NTDs. A total of 15 articles were included, selected based on methodological rigor and relevance. Data were synthesized into thematic categories, including burden, interventions, and policy. Studies revealed significant geographical and health disparities, with disruptions due to COVID-19, underfunding, and poor integration into primary care. Effective strategies included WASH integration, translational technologies, and policy alignment with Universal Health Coverage. Research gaps persist in pediatric populations and community-level participation. Addressing NTDs requires resilient, multisectoral approaches embedded within primary healthcare systems. Global efforts must prioritize equity, local adaptation, and sustainable financing to meet 2030 elimination targets.</p>