02426nas a2200325   4500000000100000008004100001260003300042653002800075653002500103653002400128653001100152100001800163700001200181700001400193700001500207700001700222700001900239700001300258700001700271700001300288700001600301700001800317700001600335245013500351856007900486300001100565490000700576520149200583022002502075       2025                            d  c12/2025bFapUNIFESP (SciELO)10aLeishmaniasis, Visceral10aCanine leishmaniasis10aOne Health approach10aBrazil1 aNascimento ER1 aRihs JB1 aElias AMS1 aCardozo ME1 aSiqueira JGA1 aMagalhães LMD1 aPires LC1 aOliveira GLD1 aBueno LL1 aFujiwara RT1 aOliveira ALGD1 aFerreira SR00aCanine leishmaniasis in the Atlantic Rainforest Biome region of Bahia, Brazil, affected by deforestation: a one health perspective  uhttps://www.scielo.br/j/rbpv/a/ZcFHpKQGwBCQrgYWtrmWFSr/?format=pdf&lang=en  a1 - 110 v343 a<p>Canine visceral leishmaniasis (CVL) is a zoonotic disease whose etiological agent is transmitted by phlebotomine sand flies, with dogs as the primary reservoir. Urbanization and deforestation have created conditions favorable to pathogen transmission. In Eunápolis, Bahia, the epidemiological situation of CVL remains entirely unknown. In this study, the prevalence of CVL and its associated socio-environmental factors were investigated. A cross-sectional study was conducted involving 243 dogs residing in both urban and rural areas. Blood samples were analyzed using the rKDDR-plus immunochromatographic test, conventional polymerase chain reaction (cPCR), and quantitative real time polymerase chain reaction (qPCR). In addition, household questionnaires were administered to assess socio-environmental conditions. Based on the rKDDR-plus serology, four samples tested positive (1.6%), and qPCR confirmed the presence of Leishmania infantum DNA in three samples (1.2%). Among the environmental factors analyzed, improper waste management (38.3%) and proximity of households to vegetation (54.7%) were notable. The detection of seropositive samples and L. infantum DNA suggests the existence of a transmission cycle of canine visceral leishmaniasis (CVL) in the studied area. In this context, public health measures, including vector control, health education initiatives, and responsible pet ownership, are essential to mitigate risks and prevent the spread of the disease.</p>
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