02896nas a2200373   4500000000100000008004100001260001200042653001700054653002500071653001400096653001000110100001000120700000900130700001000139700000900149700001100158700001100169700001000180700000900190700001100199700001300210700001400223700001000237700001000247700000900257700001000266700000900276245017100285856007500456300001100531490000700542520195900549022001402508       2026                            d  c04/202610aEpidemiology10aSnakebite envenoming10aHospitals10aChina1 aYan S1 aFu W1 aYan Z1 aHu Y1 aSong X1 aWang J1 aHao W1 aHe L1 aChen Y1 aDiané M1 aSouaré I1 aGuo W1 aBin W1 aMa Y1 aHan X1 aLv C00aClinical epidemiology of snakebite envenoming in hospitals 11 provinces of Yangtze River Basin and southern regions of China: A retrospective hospital-based analysis.  uhttps://pmc.ncbi.nlm.nih.gov/articles/PMC13119834/pdf/pntd.0013247.pdf  a1 - 180 v203 a<p><strong>BACKGROUND: </strong></p>

<p>As the largest developing country, China works towards reducing mortality and disability from snakebite envenoming (SBE) by 50% before 2030, as epidemiological evidences are essential.</p>

<p><strong>METHODS: </strong></p>

<p>A cross-sectional survey was conducted in 11 provinces in China using a multistage stratified cluster random sampling, and hospitalized snakebite victims with complete case histories from January 1, 2017, to December 31, 2021, were included.</p>

<p><strong>RESULTS: </strong></p>

<p>A total of 40,817 snakebite victims were enrolled in this study. The most common snake species were Agkistrodon halys (16.04%) and Trimeresurus stejnegeri (11.40%). However, 56.36% of the snake species remained unidentified. Furthermore, our results revealed that 60.36% of snakebite victims were males, 63.71% were older than 50 years, 59.70% were peasants, 11.14% experienced moderate envenomation on admission, and 0.64% had severe envenomation on admission. Ultimately, only 6.82% of the victims achieved complete healing, whereas 82.44% of snakebite victims demonstrated improvement in their condition upon discharge. Only 69.57% of snakebite victims received antivenom treatments. Furthermore, age, occupation, hospitalization duration, snake specie, site of bite, location, activity, envenomation on admission, clinical manifestation, and treatment significantly affected the discharge outcomes of snakebite victims.</p>

<p><strong>CONCLUSIONS: </strong></p>

<p>This study is the first large-sample investigation focusing on the epidemiological characteristics of SBE in China, addressing research gaps and filling the void in the relevant the World Health Organization data. The findings call for authorities and managers to strengthen partnerships, coordination, and resources, reduce SBE incidents, and ensure that victims receive fair, safe, and effective treatments.</p>
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