01577nas a2200193 4500000000100000008004100001260005300042653001800095653001700113653001700130653001400147653001700161100001300178700001500191245007800206490000700284520107800291022001401369 2026 d c06/2026bSpringer Science and Business Media LLC10aLeishmaniasis10aTransmission10aEpidemiology10aDiagnosis10aNorth Africa1 aTolba MM1 aBeshara MB00aLeishmaniasis in North Africa; Ecological Dynamics and Control Challenges0 v133 a

Purpose of Review

Leishmaniasis is a significant neglected tropical disease (NTD) with profound public health and socioeconomic impacts across North Africa. This review provides an emphasis on the epidemiology, transmission dynamics, and diagnostic evolution of the disease.

Recent Findings

Ecological diversity, rapid urbanization, climate change, and population displacement have reshaped transmission cycles. Cutaneous Leishmaniasis (CL) remains hyper-endemic in North Africa, while Visceral Leishmaniasis (VL) continues to cause high mortality in East Africa. Emerging molecular tools are being evaluated against current diagnostic gold standards, highlighting systemic gaps in surveillance and treatment accessibility.

Summary

This work provides essential insights on epidemiology, transmission, and diagnosis of Leishmaniasis in Egypt and other North African countries highlighting the impact of ecological and demographic factors on disease dynamics and identifying gaps in surveillance and treatment.

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