02094nas a2200217 4500000000100000008004100001653001600042653002300058653003900081100001300120700001300133700001200146700001200158700001400170700001100184245014700195300001200342490000700354520150100361022001401862 2014 d10aRisk factor10aPolicy development10aNeglected tropical diseases (NTDs)1 aMackey T1 aLiang BA1 aCuomo R1 aHafen R1 aBrouwer K1 aLee DE00aEmerging and reemerging neglected tropical diseases: a review of key characteristics, risk factors, and the policy and innovation environment. a949-9790 v273 a

In global health, critical challenges have arisen from infectious diseases, including the emergence and reemergence of old and new infectious diseases. Emergence and reemergence are accelerated by rapid human development, including numerous changes in demographics, populations, and the environment. This has also led to zoonoses in the changing human-animal ecosystem, which are impacted by a growing globalized society where pathogens do not recognize geopolitical borders. Within this context, neglected tropical infectious diseases have historically lacked adequate attention in international public health efforts, leading to insufficient prevention and treatment options. This subset of 17 infectious tropical diseases disproportionately impacts the world's poorest, represents a significant and underappreciated global disease burden, and is a major barrier to development efforts to alleviate poverty and improve human health. Neglected tropical diseases that are also categorized as emerging or reemerging infectious diseases are an even more serious threat and have not been adequately examined or discussed in terms of their unique risk characteristics. This review sets out to identify emerging and reemerging neglected tropical diseases and explore the policy and innovation environment that could hamper or enable control efforts. Through this examination, we hope to raise awareness and guide potential approaches to addressing this global health concern.

 

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