02342nas a2200301   4500000000100000008004100001653001900042653001000061653003900071653000800110653002500118100001500143700001600158700001400174700001500188700001400203700001300217700001400230700001200244700001300256700001300269700001200282245013500294856006900429300001200498490000700510520152300517       2014                            d10aNon-compliance10aNepal10aNeglected tropical diseases (NTDs)10aMDA10aLymphatic filariasis1 aAdhikari R1 aSherchand J1 aMishra SR1 aRanabhat K1 aDevkota P1 aMishra D1 aGhimire Y1 aGelal K1 aMishra R1 aPaudel R1 aothers 00aFactors determining non-compliance to mass drug administration for lymphatic filariasis elimination in endemic districts of Nepal.  uhttp://www.jnhrc.com.np/index.php/jnhrc/article/viewFile/503/444  a124-1290 v123 a<p>Background: Mass drug administration (MDA) has been implemented in Nepal since 2003 for elimination of Lymphatic Filariasis (LF). The objective of this study was to explore the factors that determine the non- compliance to MDA for Lymphatic Filariasis elimination in endemic districts of Nepal. Methods: A cross-sectional descriptive study was carried out in three endemic districts namely Dhading, Kapilvastu and Kailali. A total of 900 people were interviewed with structured questionnaire. Results: The result shows that the respondents who knew the DEC contains Albendazole (84.9% vs 42.5%, P&lt;0.001, Adjusted OR=2.89(1.946-4.29) at 95% CI), who were aware of MDA campaign (78.2% vs 33.8% P&lt;0.001, Adjusted OR=2.87(1.73-4.74) at 95% CI), who were visited by health workers at their home during MDA campaign (75.9% vs 24.1% P&lt;0.001, Adjusted OR=4.85(2.448-9.594) at 95% CI) had significantly higher compliance. The respondents who had knowledge of side effects during MDA campaign had lower prevalence of non-compliance as compared who did not have (9.4% vs 33.2%, P&lt;0.001). Conclusions: Advanced age, primary or below education, ever married, inadequate knowledge on drug, inadequate awareness on MDA, no home visit by health workers during MDA, no belief on MDA drugs were significantly associated with higher non-compliance to MDA. In future, MDA program should focus on awareness campaigns related to composition of drugs, side effects of drugs and compulsory home visit during the campaign.</p>