01459nas a2200157   4500000000100000008004100001100001300042700001100055700001500066700001200081700001400093245007600107050002100183520108300204022001401287       2015                            d1 aMurase C1 aKono M1 aNakanaga K1 aIshii N1 aAkiyama M00aBuruli ulcer successfully treated with negative-pressure wound therapy.  aMurase2014 - NTD3 a<p>This case report details successful use of negative-pressure wound therapy for treatment of an advanced Buruli ulcer and suggests that such treatment might be effective in similar future cases.</p>

<p>Buruli ulcer (BU) is a slowly progressive lesion with local necrosis caused by <em>Mycobacterium ulcerans</em>.<sup><a class="reflink" href="http://archderm.jamanetwork.com/article.aspx?articleid=2323636#dlo150017r1">1</a></sup> It is mostly seen in tropical areas,<sup><a class="reflink" href="http://archderm.jamanetwork.com/article.aspx?articleid=2323636#dlo150017r2">2</a></sup><sup>,<a class="reflink" href="http://archderm.jamanetwork.com/article.aspx?articleid=2323636#dlo150017r3">3</a></sup> and the lack of awareness of BU in nonendemic areas sometimes leads to diagnostic delay. Significant delay places patients at risk of more extensive disease. Negative-pressure wound therapy (NPWT) is considered to be a great alternative because it accelerates wound healing. Herein, we report an advanced case of BU successfully treated with NPWT.</p>

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