02205nas a2200205 4500000000100000008004100001653001000042653001900052653002300071653001100094653001600105653002500121100001200146245006100158856005600219300001500275490000800290520168700298022001401985 2014 d10aTaxes10aPrivate Sector10aInsurance Coverage10aIncome10aHealth care10aDeveloping countries1 aMills A00aHealth care systems in low- and middle-income countries. uhttp://www.nejm.org/doi/full/10.1056/NEJMra1110897  ap. 552-5570 v3703 a

Over the past 10 years, debates on global health have paid increasing attention to the importance of health care systems, which encompass the institutions, organizations, and resources (physical, financial, and human) assembled to deliver health care services that meet population needs. It has become especially important to emphasize health care systems in low- and middle-income countries because of the substantial external funding provided for disease-specific programs, especially for drugs and medical supplies, and the relative underfunding of the broader health care infrastructures in these countries.1 A functioning health care system is fundamental to the achievement of universal coverage for health care, which has been the focus of recent statements by advocacy groups and other organizations around the globe, including a declaration by the United Nations in 2012.2

Recent analyses have drawn attention to the weaknesses of health care systems in low- and middle-income countries.

In response to such deficiencies in the health care system, a number of countries and their partners in development have been introducing new approaches to financing, organizing, and delivering health care. This article briefly reviews the main weaknesses of health care systems in low- and middle-income countries, lists the most common responses to those weaknesses, and then presents three of the most popular responses for further review.

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