01953nas a2200253 4500000000100000008004100001100001600042700001300058700001300071700001200084700001400096700000900110700001300119700001500132700002000147700001200167700001300179245012200192856005300314300001400367490000700381520128800388022002301676 2015 d1 aKaatano G M1 aMin D -Y1 aSiza J E1 aT.-S. Y1 aChai J -Y1 aKo Y1 aRim H -J1 aChang S -Y1 aChangalucha J M1 aEom K S1 aRim H -J00aSchistosoma mansoni-related hepatosplenic morbidity in adult population on Kome Island, Sengerema District, Tanzania. uhttp://parasitol.kr/upload/pdf/kjp-53-5-545.pdf  a545 - 5510 v533 a

Editor's Abstract: Schistosomiasis is one of the important neglected tropical diseases (NTDs) in Tanzania, particularly in Lake Victoria zone. This baseline survey was a part of the main study of integrated control of schistosomiasis and soil-transmitted helminths (STHs) aimed at describing morbidity patterns due to intestinal schistosomiasis among adults living on Kome Island, Sengerema District, Tanzania. Total 388 adults from Kome Islands (about 50 people from each village) aged between 12 and 85 years, were examined by abdominal ultrasound according to the Niamey protocol. Liver image patterns (LIPs) A and B were considered normal, and C-F as distinct periportal fibrosis (PPF). The overall prevalence of PPF was 42.2%; much higher in males than in females (47.0% in male vs 34.4% in females, P=0.007). Abnormal increase of segmental branch wall thickness (SBWT) and dilated portal vein diameter (PVD) were also more common in males than in females. Hepatosplenomegaly was frequently encountered; 68.1% had left liver lobe hepatomegaly and 55.2% had splenomegaly. Schistosoma mansoni-related morbidity is quite high among adults in this community justifying the implementation of integrated control strategies through mass drug

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