02076nas a2200409 4500000000100000008004100001653001800042653001400060653000900074653001200083653002000095653002400115653001500139653001500154653000900169653001000178653001200188653001100200653002400211653001100235653001000246653002500256653001500281653001200296653001500308100001500323700001300338700001400351700001300365700001600378245015400394856004700548300001100595490000700606520103900613022001401652 2013 d10aWater Quality10aTrichuris10aSoil10aSchools10aschistosomiasis10aSchistosoma mansoni10aSanitation10aPrevalence10aMale10aKenya10aHygiene10aHumans10aHookworm Infections10aFemale10aChild10aAscaris lumbricoides10aAscariasis10aAnimals10aAdolescent1 aFreeman MC1 aClasen T1 aBrooker S1 aAkoko DO1 aRheingans R00aThe impact of a school-based hygiene, water quality and sanitation intervention on soil-transmitted helminth reinfection: a cluster-randomized trial. uhttp://www.ajtmh.org/content/89/5/875.long a875-830 v893 a

We conducted a cluster-randomized trial to assess the impact of a school-based water treatment, hygiene, and sanitation program on reducing infection with soil-transmitted helminths (STHs) after school-based deworming. We assessed infection with STHs at baseline and then at two follow-up rounds 8 and 10 months after deworming. Forty government primary schools in Nyanza Province, Kenya were randomly selected and assigned to intervention or control arms. The intervention reduced reinfection prevalence (odds ratio [OR] 0.56, 95% confidence interval [CI] 0.31-1.00) and egg count (rate ratio [RR] 0.34, CI 0.15-0.75) of Ascaris lumbricoides. We found no evidence of significant intervention effects on the overall prevalence and intensity of Trichuris trichiura, hookworm, or Schistosoma mansoni reinfection. Provision of school-based sanitation, water quality, and hygiene improvements may reduce reinfection of STHs after school-based deworming, but the magnitude of the effects may be sex- and helminth species-specific.

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