02652nas a2200397   4500000000100000008004100001653001100042653001600053653002000069653003700089653001900126653002900145653001600174653000900190653001100199653001100210653002600221653001500247653002800262653001900290653002200309653000900331653001000340653003100350100001300381700001900394700001600413700002000429700001400449700001400463245011300477300000900590490000800599520163300607022001402240       2013                            d10aStroke10aSample Size10aQuality of Life10aPsychiatric Status Rating Scales10aPilot Projects10aNeuropsychological Tests10aMiddle Aged10aMale10aHumans10aFemale10aDisability Evaluation10aDepression10aCross-Sectional Studies10aChagas disease10aAged, 80 and over10aAged10aAdult10aActivities of Daily Living1 aSouza AC1 aCosta Rocha MO1 aTeixeira AL1 aDias Júnior JO1 aSousa LAP1 aNunes MCP00aDepressive symptoms and disability in chagasic stroke patients: impact on functionality and quality of life.  a34-70 v3243 a<p><strong>INTRODUCTION: </strong>Chagas disease (CD) is associated with stroke, which can result in significant long-term disability. Stroke has also been associated with depressive symptoms, which affect functional performance and quality of life (QOL). Few data are available on the effect of chagasic stroke on functional performance and QOL.</p>

<p><strong>OBJECTIVES: </strong>This study aimed to investigate the correlation of stroke disability and depressive symptoms with functional performance and QOL in chagasic stroke patients.</p>

<p><strong>METHODS: </strong>In this cross-sectional study, stroke sequelae were assessed using the Modified Rankin Stroke Scale (MRSS), depressive symptoms using the Beck Depression Inventory (BDI), functional performance using the Barthel Index (BI), and QOL using the WHOQOL-BREF.</p>

<p><strong>RESULTS: </strong>Twenty-one patients with CD and a previous diagnosis of stroke were included. There was a correlation between the MRSS score and the BI score (r=-0.663, p=0.003), but not the scores of the WHOQOL-BREF subscales. The BDI score was correlated with the WHOQOL-BREF subscale scores (Physical: r=-0.733, p=0.001; Psychological: r=-0.581, p=0.012; Social: r=-0.713, p=0.001; Environmental: r=-0.659, p=0.003). However, the BDI score was not associated with the BI score (r=0.279, p=0.262).</p>

<p><strong>CONCLUSIONS: </strong>QOL in patients with CD appears to be influenced more by depressive symptoms than by the motor-associated consequences of stroke. Conversely, motor sequelae impair the functionality of the patient more than depressive symptoms.</p>
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