01869nas a2200229   4500000000100000008004100001100001200042700001100054700001200065700001100077700001200088700001400100700001200114700001100126700001200137245005900149856007400208300001000282490000600292520132700298022001401625       2015                            d1 aChoo SW1 aAng MY1 aDutta A1 aTan SY1 aSiow CC1 aHeydari H1 aMutha N1 aWee WY1 aWong GJ00aMycoCAP - Mycobacterium comparative analysis platform.  uhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678330/pdf/srep18227.pdf  a182270 v53 a<p>Mycobacterium spp. are renowned for being the causative agent of diseases like leprosy, Buruli ulcer and tuberculosis in human beings. With more and more mycobacterial genomes being sequenced, any knowledge generated from comparative genomic analysis would provide better insights into the biology, evolution, phylogeny and pathogenicity of this genus, thus helping in better management of diseases caused by Mycobacterium spp.With this motivation, we constructed MycoCAP, a new comparative analysis platform dedicated to the important genus Mycobacterium. This platform currently provides information of 2108 genome sequences of at least 55 Mycobacterium spp. A number of intuitive web-based tools have been integrated in MycoCAP particularly for comparative analysis including the PGC tool for comparison between two genomes, PathoProT for comparing the virulence genes among the Mycobacterium strains and the SuperClassification tool for the phylogenic classification of the Mycobacterium strains and a specialized classification system for strains of Mycobacterium abscessus. We hope the broad range of functions and easy-to-use tools provided in MycoCAP makes it an invaluable analysis platform to speed up the research discovery on mycobacteria for researchers. Database URL: http://mycobacterium.um.edu.my.</p>
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