01559nas a2200277   4500000000100000008004100001653001700042653002500059653001700084653002300101653001400124653002300138653001400161653001300175653001400188653002700202100001300229700001100242700001600253700001200269700001000281245009600291490000700387520087300394022001401267       2016                            d10aTherapeutics10aPrevention & control10aParasitology10aParasitic Diseases10aParasites10aNeglected Diseases10aHelminths10aEpilepsy10adiagnosis10aCentral Nervous System1 aCarpio A1 aRomo M1 aParkhouse M1 aShort B1 aDua T00aParasitic diseases of the central nervous system: lessons for clinicians and policy makers.0 v163 a<p>Parasitic diseases of the central nervous system are associated with high mortality and morbidity, especially in resource-limited settings. The burden of these diseases is amplified as survivors are often left with neurologic sequelae affecting mobility, sensory organs, and cognitive functions, as well as seizures/epilepsy. These diseases inflict suffering by causing lifelong disabilities, reducing economic productivity, and causing social stigma. The complexity of parasitic life cycles and geographic specificities, as well as overlapping clinical manifestations in the host reflecting the diverse pathogenesis of parasites, can present diagnostic challenges. We herein provide an overview of these parasitic diseases and summarize clinical aspects, diagnosis, therapeutic strategies and recent milestones, and aspects related to prevention and control.</p>
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