01255nas a2200205   4500000000100000008004100001653003000042653001700072653001300089653001200102100001300114700001200127700001100139700001400150245006900164856008700233490000700320520070900327022001301036       2016                            d10aZero leprosy transmission10aTransmission10aStrategy10aleprosy1 aSmith WC1 aAerts A1 aKita E1 aVirmond M00aTime to define leprosy elimination as zero leprosy transmission?  uhttp://www.thelancet.com/journals/laninf/article/PIIS1473-3099(16)00087-6/fulltext0 v163 a<p>In 1982, in response to growing evidence of resistance to the antibacterial drug, dapsone, WHO recommended that all patients with leprosy be treated with a short-course combination of three antibacterial drugs, rifampicin, dapsone, and clofazimine.<sup>1</sup> This multidrug therapy reduced the number of patients with leprosy being treated from 5·3 million in 1985 to 3·1 million in 1991.<sup>2</sup> The reduction in prevalence inspired the World Health Assembly in 1991 to set a target to eliminate leprosy as a public health problem by 2000, defining elimination as a global prevalence rate below one case per 10 000 of the population.</p>

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