01401nas a2200205 4500000000100000008004100001653001500042653001000057100001300067700001300080700001200093700001300105700001400118245005400132856006100186300001100247490000700258520091600265022001401181 2015 d10aZika virus10aNepal1 aDhimal M1 aGautam I1 aBaral G1 aPandey B1 aKarki K B00aZika virus: Yet another emerging threat to Nepal. uhttp://www.jnhrc.com.np/index.php/jnhrc/article/view/686 a248-510 v133 a

Zika virus (ZIKV) is a flavivirus with single stranded RNA related to yellow fever, dengue, West Nile, and Japanese encephalitis viruses and is transmitted by Aedes mosquitoes primarily by Aedes aegipti which is widely distributed in Nepal. ZIKV was first identified incidentally in Rhesus monkey in Uganda in 1947 and human infection in 1952; and by now outbreaks of ZIKV disease have been recorded in Africa, the Americas, Asia and the Pacific. The World Health Organization (WHO) has recently declared the ZIKV an international public health emergency. The aim of this paper is to briefly summarize origin, signs, symptoms, transmission, diagnosis, preventions and management of ZIKV and possible threat to Nepal in light of endemicity of other arbovirus infections and common mosquito vector species in Nepal. Keyword: Aedes aegypti; aedes albopictus; zika virus; microcephaly; birth defect; Nepal.

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