01224nas a2200157   4500000000100000008004100001653002300042653002300065653001700088100001500105700001900120245009200139490000700231520081400238022001401052       2016                            d10aParasitic Diseases10aDrug repositioning10aClinical use1 aFerreira L1 aAndricopulo AD00aDrug repositioning approaches to parasitic diseases: a medicinal chemistry perspective.0 v213 a<p>Identifying new indications for clinically useful drugs is a worthwhile approach for neglected tropical diseases. The number of successful repurposing cases in the field is growing as not-for-profit organizations, in association with academia and pharmaceutical companies, enable screening campaigns for the identification of new repositioning candidates. Current programs have delivered encouraging results as the use of state-of-the-art technologies, such as genomic and structural biology tools, and high-throughput screening platforms have become increasingly common in infectious disease research. Drug repositioning has played a key part in improving the lives of those suffering from these conditions, as evidenced by successful precedents and recent studies on preeminent parasitic disorders.</p>
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