01544nas a2200301 4500000000100000008004100001653003900042653002900081653002400110653002300134653003400157653002000191100001100211700001100222700001400233700001600247700001400263700001200277700001400289700001500303700001600318700001500334245021300349300001000562490000600572520065000578022001401228 2016 d10aNeglected tropical diseases (NTDs)10aMass drug administration10aHelminth infections10aSub-Saharan Africa10aCommunity based interventions10aDisease control1 aDean L1 aPage S1 aHawkins K1 aStothard RJ1 aThomson R1 aWanji S1 aGyapong M1 aAnagbogu I1 aMolyneux DH1 aTheobald S00aTailoring mass drug administration to context: implementation research is critical in achieving equitable progress in the control and elimination of helminth neglected tropical diseases in sub-Saharan Africa. a233-40 v83 a

The concept of a technological quick fix or 'magic-bullet' for control and elimination of Neglected Tropical Diseases (NTDs) is flawed. NTDs are embedded within complex biological and social systems that are shaped by ecological and political contexts. This commentary emphasises the need for implementation research to address implementation gaps in the control of NTDs. With a specific focus on sub-Saharan Africa and helminth diseases amenable to preventive chemotherapy through mass drug administration, we explore the important role of context, programme partnerships and community in achieving equitable and effective NTD control.

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