01133nas a2200229   4500000000100000008004100001653002200042653003900064653002300103653001100126653001900137653002500156100001500181700001100196700001200207245007500219856009000294300001000384490000600394520048900400022001400889       2011                            d10aTropical Medicine10aPublic-Private Sector Partnerships10aNeglected Diseases10aHumans10aDrug Discovery10aAntiparasitic Agents1 aJakobsen P1 aWang M1 aNwaka S00aInnovative partnerships for drug discovery against neglected diseases.  uhttp://journals.plos.org/plosntds/article/asset?id=10.1371%2Fjournal.pntd.0001221.PDF  ae12210 v53 a<p>There is a compelling scarcity of pharmaceutical agents for efficacious, safe, and affordable treatment of neglected infectious or tropical diseases such as malaria, trypanosomiasis, leishmaniasis, dengue, lymphatic filariasis, and soil-transmitted helminths, despite their high prevalence in the developing world. Toxicity of drugs, microbial resistance patterns, and long courses of treatments are among the current challenges in effective management of neglected diseases.</p>
  a1935-2735