03225nas a2200529   4500000000100000008004100001653002100042653001700063653002300080653002300103653001100126653002600137653003500163100001400198700001300212700001300225700001200238700001400250700001100264700001100275700001600286700001500302700001400317700001400331700001300345700001700358700001500375700001900390700001500409700001700424700001300441700001300454700001200467700001500479700001300494700001600507700001000523700001800533700001100551700001500562245015500577856009000732300001000822490000600832520184300838022001402681       2012                            d10aTropical Climate10aParasitology10aParasitic Diseases10aNeglected Diseases10aHumans10aEpidemiologic Methods10aClinical Laboratory Techniques1 aSolomon A1 aEngels D1 aBailey R1 aBlake I1 aBrooker S1 aChen J1 aChen J1 aChurcher TS1 aDrakeley C1 aEdwards T1 aFenwick A1 aFrench M1 aGabrielli AF1 aGrassly NC1 aHarding-Esch E1 aHolland MJ1 aKoukounari A1 aLammie P1 aLeslie J1 aMabey D1 aRhajaoui M1 aSecor EW1 aStothard RJ1 aWei H1 aWillingham LA1 aZhou X1 aPeeling RW00aA diagnostics platform for the integrated mapping, monitoring, and surveillance of neglected tropical diseases: rationale and target product profiles.  uhttp://journals.plos.org/plosntds/article/asset?id=10.1371%2Fjournal.pntd.0001746.PDF  ae17460 v63 a<p>Control and elimination strategies for trachoma, lymphatic filariasis, onchocerciasis, schistosomiasis, ascariasis, trichuriasis and hookworm infection have striking similarities, including the use of periodic mass drug administration (MDA). Because these diseases tend to be co-endemic in the poorest communities of the poorest countries, such that multiple NTDs are frequently found not just in the same populations but within the same individuals <a class="ref-tip" href="http://journals.plos.org/plosntds/article?id=10.1371%2Fjournal.pntd.0001746#pntd.0001746-Steinmann1">[1]</a>, it has been suggested that mapping, treatment, impact monitoring, and post-elimination surveillance could be coordinated to better utilise limited human and financial resources. Although many programmes now distribute multiple anthelmintics simultaneously, progress in integrating mapping <a class="ref-tip" href="http://journals.plos.org/plosntds/article?id=10.1371%2Fjournal.pntd.0001746#pntd.0001746-Brooker1">[2]</a>, <a class="ref-tip" href="http://journals.plos.org/plosntds/article?id=10.1371%2Fjournal.pntd.0001746#pntd.0001746-Kolaczinski1">[3]</a>, <a class="ref-tip" href="http://journals.plos.org/plosntds/article?id=10.1371%2Fjournal.pntd.0001746#pntd.0001746-Brooker2">[4]</a>, monitoring, and surveillance <a class="ref-tip" href="http://journals.plos.org/plosntds/article?id=10.1371%2Fjournal.pntd.0001746#pntd.0001746-Bergquist1">[5]</a> activities has been slow <a class="ref-tip" href="http://journals.plos.org/plosntds/article?id=10.1371%2Fjournal.pntd.0001746#pntd.0001746-Baker1">[6]</a>. Ideally, population sampling strategies, fieldwork protocols, and sample types (e.g., blood or urine) could all be harmonised between diseases to increase population compliance, simplify overall survey procedures, and decrease costs.</p>
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