01920nas a2200337   4500000000100000008004100001653003900042653001800081653002000099653001100119653001000130100001000140700001000150700001100160700001000171700001100181700001000192700000900202700001200211700000900223700001100232700001100243700000900254700001200263245010000275856009000375300001300465490000700478520108300485022001401568       2016                            d10aNeglected tropical diseases (NTDs)10aInterventions10aDisease control10aDengue10aChina1 aLin H1 aLiu T1 aSong T1 aLin L1 aXiao J1 aLin J1 aHe J1 aZhong H1 aHu W1 aDeng A1 aPeng Z1 aMa W1 aZhang Y00aCommunity involvement in dengue outbreak control: An integrated rigorous intervention strategy.  uhttp://journals.plos.org/plosntds/article/asset?id=10.1371%2Fjournal.pntd.0004919.PDF  ae00049190 v103 a<p><strong>BACKGROUND: </strong>An explosive outbreak of dengue fever occurred in Guangdong Province, China in 2014. A community-based integrated intervention was applied to control this outbreak in the capital city Guangzhou, where dengue epidemic was mainly caused by imported cases.</p>

<p><strong>METHODOLOGY/PRINCIPAL FINDINGS: </strong>We used a time series generalized additive model based on meteorological factors to assess the effectiveness of this intervention. The results showed that there was significant reduction in mosquito density following the intervention, and there was a 70.47% (95% confidence interval: 66.07%, 74.88%) reduction in the reported dengue cases compared with the predicted cases after 12 days since the beginning of the intervention, we estimated that a total of 23,302 dengue cases were prevented.</p>

<p><strong>CONCLUSIONS: </strong>This study suggests that an integrated dengue intervention program has significant effects to control a dengue outbreak in areas where dengue epidemic was mainly caused by imported dengue cases.</p>
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