02741nas a2200409   4500000000100000008004100001653001800042653001500060653003100075653002400106653002800130653002500158653002300183653001600206653000900222653001100231653001100242653001200253653001300265653002500278653001700303653002600320653003100346100001200377700001400389700001200403700001200415700001100427700001600438700001100454245009200465856007700557300001000634490000800644520166500652022001402317       2011                            d10aVisual Acuity10aTrichiasis10aSurveys and Questionnaires10aSingle-Blind Method10aSickness Impact Profile10aSecondary Prevention10aPostoperative Care10aMiddle Aged10aMale10aHumans10aFemale10aEyelids10aEthiopia10aCase-Control Studies10aAzithromycin10aAnti-Bacterial Agents10aActivities of Daily Living1 aWolle M1 aCassard S1 aGower E1 aMunoz B1 aWang J1 aAlemayehu W1 aWest S00aImpact of Trichiasis surgery on physical functioning in Ethiopian patients: STAR trial.  uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079795/pdf/nihms256547.pdf  a850-70 v1513 a<p><strong>PURPOSE: </strong>To evaluate the physical functioning of Ethiopian trichiasis surgery patients before and 6 months after surgery.</p>

<p><strong>DESIGN: </strong>Nested cohort study.</p>

<p><strong>METHODS: </strong>This study was nested within the Surgery for Trichiasis, Antibiotics to Prevent Recurrence (STAR) clinical trial conducted in Ethiopia. Demographic information, ocular examinations, and physical functioning assessments were collected before and 6 months after surgery. A single score for patients' physical functioning was constructed using Rasch analysis. A multivariate linear regression model was used to determine if change in physical functioning was associated with change in visual acuity.</p>

<p><strong>RESULTS: </strong>Of the 438 participants, 411 (93.8%) had both baseline and follow-up questionnaires. Physical functioning scores at baseline ranged from -6.32 (great difficulty) to +6.01 (no difficulty). The percentage of participants reporting no difficulty in physical functioning increased by 32.6%; the proportion of participants in the mild/no visual impairment category increased by 8.6%. A multivariate linear regression model showed that for every line of vision gained, physical functioning improves significantly (0.09 units; 95% CI: 0.02-0.16).</p>

<p><strong>CONCLUSIONS: </strong>Surgery to correct trichiasis appears to improve patients' physical functioning as measured at 6 months. More effort in promoting trichiasis surgery is essential, not only to prevent corneal blindness, but also to enable improved functioning in daily life.</p>

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