02640nas a2200349 4500000000100000008004100001653003000042653001800072653002100090653001700111653002800128653002100156653002000177653001800197653001600215653000900231653001100240653001800251653001100269653002200280653000900302653001000311653001500321100001400336700001400350700001300364245008700377300001200464490000700476520179300483022001402276 2014 d10aVisually Impaired Persons10aVisual Acuity10aVision Disorders10aSouth Africa10aSickness Impact Profile10aRural Population10aQuality of Life10aPsychometrics10aMiddle Aged10aMale10aHumans10aHealth Status10aFemale10aAged, 80 and over10aAged10aAdult10aAdolescent1 aBriesen S1 aRoberts H1 aFinger R00aThe impact of visual impairment on health-related quality of life in rural Africa. a297-3060 v213 a

PURPOSE: To assess the impact of visual impairment (VI) on utility values in Sub-Saharan Africa and compare findings with other studies from low- and high-income countries.

METHODS: Patients with normal vision and various levels of VI were recruited from a secondary eye clinic in rural Kenya and interviewed using time trade-off (TTO). VI was classified using the World Health Organization definition of (normal vision, visual acuity ≥20/60, VI 20/80-20/200, severe VI 20/240-20/400, and blindness <20/400).

RESULTS: Mean age of the total sample (N = 303) was 50.3 years (standard deviation, SD, ±18.17 years), and 51.5% of patients were male. Most were small-scale farmers and illiteracy was high at 40%. Mean TTO scores per group were: normal vision 0.93 (SD ± 0.10), VI 0.88 (SD ± 0.14), severe VI 0.86 (SD ± 0.13), blindness 0.73 (SD ± 0.17; p ≤ 0.001). Lower TTO scores were independently associated with worse visual acuity (p ≤ 0.001), longer duration of disease (p ≤ 0.001) and illiteracy (p = 0.011), but not with cause of VI, age, sex, marital status, socioeconomic status, or systemic comorbidities in multivariate analyses. Overall, TTO scores were considerably higher than those reported from high-income countries at similar levels of VI.

CONCLUSION: In this rural African population, duration and extent of vision loss, rather than cause, socioeconomic factors and comorbidities affected vision-related quality of life. Our findings underline the importance of providing sight-restoring treatment as timely as possible and the necessity of enhancing rehabilitation efforts for those with non-curable eye diseases.

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