02897nas a2200349 4500000000100000008004100001653001100042653003000053653001300083653002100096653001800117653002600135653001900161653000900180653003000189653001100219653002200230653001100252653001000263653002600273653001000299100001300309700001200322700001300334700001300347700001500360245010000375300001100475490000700486520204000493022001402533 2006 d10aZambia10aWorld Health Organization10aTrachoma10aRural Population10aRoxithromycin10aRetrospective Studies10aMass Screening10aMale10aInternational Cooperation10aHumans10aFollow-Up Studies10aFemale10aChild10aAnti-Bacterial Agents10aAdult1 aAstle WF1 aWiafe B1 aIngram A1 aMwanga M1 aGlassco CB00aTrachoma control in Southern Zambia--an international team project employing the SAFE strategy. a227-360 v133 a

PURPOSE: To determine the prevalence of trachoma and to measure the impact of the SAFE strategy (World Health Organization GET 2020 strategy) for treating trachoma in the Gwembe District of Southern Zambia.

DESIGN: This is an observational study of the introduction of the SAFE strategy employing a collaborative approach and its impact on trachoma in the area.

PARTICIPANTS: Three thousand eight hundred ninety two persons in communities at 26 well sites in the Gwembe district of Southern Zambia were included in this study.

METHODS: New, clean water wells were drilled under local supervision for each of 26 identified villages. All people living in villages near the wells were screened for trachoma and then treated with antibiotic if required. Education on personal and environmental hygiene was provided by trained volunteers. Patients affected by trichiasis and corneal scarring received surgery, locally if possible. Attempts to control fly populations by cleaning villages, penning livestock, and digging latrines were undertaken. This was performed under advisement and consultation with local villagers and government officials. Data was collected on variables normally associated with trachoma and others relating to demographics, water quality, environment and hygiene.

MAIN OUTCOME MEASURES: Prevalence of trachoma in the area at two years post introduction of SAFE strategy.

RESULTS: The overall prevalence of trachoma in the area was 47% in 2001; however, the prevalence was 55% among children under 10 years. At two years post intervention, the overall prevalence of trachoma reduced to 7.6%, and decreased to 10.6% in children under 10 years, and 5.9% among adults.

CONCLUSIONS: Continued monitoring and risk factors will need to continue to be addressed in order to sustain this trachoma control project in this area of Zambia.

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